Scientific excellence as a discipline
Scientific rigor, quality, and originality are the selection criteria applied to the research programs considered by the Foundation’s steering committee. The Foundation’s mandate also includes the encouragement of inter-institutional, interdisciplinary, and public-private projects, among others...
• Inter-institutional projects are designed to maximize the synergies of the research laboratories of the ENS, the ESPCI, and the Curie Institute.
• Interdisciplinary projects are intended to shorten the discovery/innovation cycle, by interfacing physics with biology and chemistry.
• Public-Private projects facilitate the implementation of the scientific partnerships that support the research efforts and the rapid development of the innovations. These projects should lead to specific applications in the health field, including mastery of natural and pathological tissue dynamics; new diagnostic tests; medical imaging systems; targeted therapeutic systems; new biotechnologies; new analytical devices; new neurosensory modeling methods; and biomimetic chemistry…
The space between macromolecules size and cel or tissue on the scale from 100 nanometers to 50 microns is where certain major biological events take place: tumor stability, neural communication, and cell adhesion…
The study of all of these events requires a multidisciplinary approach, and is taking on the major challenge of achieving cooperation among very diverse cultures, e.g., those of physicians, biostatisticians, chemists, biologists, and pharmacologists. Over the last 40 years, the Foundation’s teams have developed unique skills in the study and modeling of the events that occur at these so-called “intermediate scales.”
These skills place the researchers in an ideal position for a concrete approach to Translational Research, because the “intermediate scales” are the locus of most of the causes of failure for standard therapeutic development strategies. These scales may thus make it possible to align animal models with clinical observations. Consequently, the researchers of the Fondation Pierre-Gilles de Gennes for Research are resolutely embracing this field of exploration, which has often been overlooked but which is of the utmost importance for the therapeutic successes of tomorrow.